Dolutegravir Plus Lamivudine Dual Therapy in Treatment Naïve HIV-1 Patients

PHASE2CompletedINTERVENTIONAL
Enrollment

122

Participants

Timeline

Start Date

December 8, 2015

Primary Completion Date

February 28, 2017

Study Completion Date

September 26, 2017

Conditions
HIV-1 Infection
Interventions
DRUG

Dolutegravir

Participants were prescribed 50 mg of DTG orally daily

DRUG

Lamivudine

Participants were prescribed 300 mg of 3TC orally daily.

Trial Locations (26)

10011

Cornell CRS (7804), New York

Weill Med. College of Cornell Univ., The Cornell CTU -Chelsea (7803), New York

10032

Columbia Physicians and Surgeons CRS (30329), New York

14642

University of Rochester Adult HIV Therapeutic Strategies Network CRS (31787), Rochester

19104

Hosp. of the Univ. of Pennsylvania CRS (6201), Philadelphia

27401

Greensboro CRS (3203), Greensboro

27516

3201 Chapel Hill CRS, Chapel Hill

30308

The Ponce de Leon Center CRS (5802), Atlanta

33136

Univ. of Miami AIDS CRS (901), Miami

37204

Vanderbilt Therapeutics CRS (3652), Nashville

43210

The Ohio State Univ. AIDS CRS (2301), Columbus

45267

Univ. of Cincinnati CRS (2401), Cincinnati

60611

Northwestern University CRS (2701), Chicago

60612

Rush Univ. Med. Ctr. ACTG CRS (2702), Chicago

63110

Washington University CRS (2101), St Louis

75208

31443 Trinity Health and Wellness Center CRS, Dallas

77030

Houston AIDS Research Team CRS (31473), Houston

80045

University of Colorado Hospital CRS (6101), Aurora

90033

University of Southern California CRS (1201), Los Angeles

90095

UCLA CARE Center CRS (601), Los Angeles

90502

Harbor-UCLA Med. Ctr. CRS (603), Torrance

92103

Ucsd, Avrc Crs (701), San Diego

02114

Massachusetts General Hospital ACTG CRS (101), Boston

02115

Brigham and Women's Hosp. ACTG CRS (107), Boston

02906

The Miriam Hospital ACTG CRS (2951), Providence

00935

Puerto Rico-AIDS CRS (5401), San Juan

All Listed Sponsors
collaborator

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

lead

Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

NETWORK

NCT02582684 - Dolutegravir Plus Lamivudine Dual Therapy in Treatment Naïve HIV-1 Patients | Biotech Hunter | Biotech Hunter