Pembrolizumab in Untreated Extensive SCLC

PHASE2CompletedINTERVENTIONAL
Enrollment

125

Participants

Timeline

Start Date

December 8, 2017

Primary Completion Date

September 22, 2020

Study Completion Date

June 22, 2022

Conditions
Small Cell Lung Cancer (SCLC)
Interventions
DRUG

Pembrolizumab

IV infusion at the dose of 200 mg on day 1 every 3 weeks

DRUG

cis/carboplatin and etoposide

Cisplatin 80 mg/m2 or Carboplatin Area Under the Curve (AUC) 5 IV infusion on day 1 Etoposide 100 mg/m2 IV infusion on day 1, 2 and 3

Trial Locations (18)

10043

Ospedale S. Luigi Gonzaga - Universita Di Torino, Orbassano

12100

Santa Croce e Carle General Hospital, Cuneo

13015

Assistance Publique - Hopitaux de Marseille - Hopital Nord, Marseille

14076

Centre Regional Francois Baclesse, Caen

20141

Istituto Europeo di Oncologia, Milan

20142

Ospedale San Paolo, Milan

29200

CHU de Brest, Brest

50134

Azienda Ospedaliero-Universitaria Careggi, Florence

67065

Centre Paul Strauss, Strasbourg

69008

Centre Leon Berard, Lyon

74370

Centre Hospitalier D'Annecy, Metz-Tessy

84902

Centre Hospitalier d'Avignon - Hopital Duffaut, Avignon

93009

Assistance Publique - Hopitaux de Paris - Hopital Avicenne, Paris

94010

Centre Hopitalier Intercommunal De Creteil, Créteil

94805

Gustave Roussy, Villejuif

95126

Ospedale Cannizzaro, Catania

M20 4BX

The Christie NHS Foundation Trust, Manchester

S10 2SJ

Sheffield Teaching Hospitals NHS Foundation Trust - Weston Park Hospital, Sheffield

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

European Organisation for Research and Treatment of Cancer - EORTC

NETWORK

NCT02580994 - Pembrolizumab in Untreated Extensive SCLC | Biotech Hunter | Biotech Hunter