PTH And Calcium Responses to Exercise in Older Adults Experiment 2 (PACE Sr. 2)

NACompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

November 30, 2015

Primary Completion Date

July 31, 2024

Study Completion Date

July 31, 2025

Conditions
Osteoporosis
Interventions
DRUG

Calcium Chloride/Calcium Gluconate

Calcium (as either calcium chloride or calcium gluconate in half normal saline) will be delivered via IV during exercise to keep serum ionized calcium levels above baseline. The clamp is modeled after the hyperglycemic glucose clamp.

DRUG

Half-Normal Saline

This is the placebo comparative infusion. Half-normal saline will be infused at the second collection visit following the identical infusion schedule determined during the calcium infusion visit.

Trial Locations (1)

80045

University of Colorado Hospital, Aurora

All Listed Sponsors
collaborator

National Center for Advancing Translational Sciences (NCATS)

NIH

lead

University of Colorado, Denver

OTHER

NCT02580604 - PTH And Calcium Responses to Exercise in Older Adults Experiment 2 (PACE Sr. 2) | Biotech Hunter | Biotech Hunter