Chemotherapy Alone vs. Chemotherapy + Surgical Resection in Patients With Limited-metastatic Adenocarcinoma of the Stomach or Esophagogastric Junction

2600 mg/m², d1 i.v., every 2 weeks

200 mg/m², d1, i.v., every 2 weeks

85 mg/m², d1, i.v., every 2 weeks

50mg/m², d1, i.v., every 2 weeks

4 mg/kg BW (6 mg loading dose at 1st administration), i.v. for 1 h, d1, i.v., every two weeks

can be used to replace leucovorin (calcium folinate)

Aim of surgical resection is a complete (R0) resection of the primary tumor and the metastases or a complete macroscopic cytoreduction of the metastases.