Bone Histomorphometry in Postmenopausal Men and Women With Osteoarthritis Undergoing Total Hip Replacement

PHASE4CompletedINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

December 22, 2015

Primary Completion Date

December 18, 2017

Study Completion Date

December 18, 2017

Conditions
Osteoporosis
Interventions
OTHER

Tetracycline

Treatment during cycle 1 consists of a total oral dose of 1000 mg of tetracycline daily for a total of 3 days.

OTHER

Demeclocycline

Treatment during cycle 2 consists of a total oral dose of 600 mg of demeclocycline daily for 3 days.

PROCEDURE

Total Hip Replacement

Participants entering this study were prescheduled to undergo elective THR due to osteoarthritis. Surgery was to be performed according to local standard of care. During THR a fragment of femoral bone was acquired for histomorphometry evaluation.

Trial Locations (2)

10993

Helen Hayes Hospital, West Haverstraw

Research Site, West Haverstraw

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Amgen

INDUSTRY