88
Participants
Start Date
March 30, 2016
Primary Completion Date
March 31, 2018
Study Completion Date
March 12, 2018
Determination of apelin and inflammatory cytokines
A blood sample will be conducted at baseline, on day 1 and day 7 post operative to meter inflammatory cytokines (IL1B, IL1-ra, IL6) and apelin.
Assessment of cognitive functions
Evaluation of preoperative cognitive performance by achieving a IQCODE, an MMS and an IADL scale.
Liquid sampling cerebrospinal
Determination of the concentrations of inflammatory cytokines and apelin in cerebrospinal fluid perioperatively.
Postoperative delirium research
Using the scale Confusion Assessment Method (CAM) for screening and delirium diagnosis. This research will be daily lasted, during the first 7 days postoperative.
Residual cognitive dysfunction research
Evaluation of postoperative cognitive performance by achieving a IQCODE, an MMS and an IADL scale realised on day 1 and day 7 postoperative. Realization of the IQCODE and IADL three months after the operation in a telephone interview.
CHU Toulouse, service d'orthopédie et traumatologie, Toulouse
University Hospital, Toulouse
OTHER