62
Participants
Start Date
September 1, 2016
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2025
alveolar recruitment maneuvers group 1
"Patients are randomized to receive in cross-over 2 ARM: CPAP at first and then eSigh.~The continuous positive airway pressure, or CPAP with application of a positive pressure of 40 cmH2O for 40 seconds without tidal volume.~The eSigh or extended sigh with increase of PEEP for 10 minutes to maintain plateau pressure at 40 cmH2O. During ARM, the peak pressure is limited to 50 cmH2O with decrease of tidal volume (Vt) if necessary.~The following data: PtiO2, respiratory parameters, systemic and intracerebral hemodynamic parameters are collected before, after 1 minute, 10 minutes and 60 minutes for each ARM."
alveolar recruitment maneuvers group 2
"Patients are randomized to receive in cross-over 2 ARM: eSigh at first and then CPAP.~The eSigh or extended sigh with increase of PEEP for 10 minutes to maintain plateau pressure at 40 cmH2O. During ARM, the peak pressure is limited to 50 cmH2O with decrease of tidal volume (Vt) if necessary.~The continuous positive airway pressure, or CPAP with application of a positive pressure of 40 cmH2O for 40 seconds without tidal volume.~The following data: PtiO2, respiratory parameters, systemic and intracerebral hemodynamic parameters are collected before, after 1 minute, 10 minutes and 60 minutes for each ARM."
RECRUITING
UH Toulouse, Toulouse
RECRUITING
UH Montpellier, Montpellier
RECRUITING
UH Nantes, Nantes
RECRUITING
UH Clermont-Ferrand, Clermont-Ferrand
RECRUITING
UH Caen, Caen
University Hospital, Toulouse
OTHER