Near-Infrared Fluorescence Guided Robotic Pulmonary Segmentectomy for Early Stage Lung Cancer

PHASE1RecruitingINTERVENTIONAL
Enrollment

250

Participants

Timeline

Start Date

October 31, 2016

Primary Completion Date

October 31, 2026

Study Completion Date

December 31, 2026

Conditions
Non-small Cell Lung Cancer
Interventions
DRUG

indocyanine green

ICG will be prepared as a sterile solution (2.5 mg/10mL) for injection. After vascular ligation, a 6 to 8mL bolus of ICG solution will be injected into the peripheral vein catheter, followed by a 10mL saline solution bolus. The Firefly camera will then be used for the NIF imaging. It is expected that the entire lung, except the segment which was previously isolated from blood supply, will fluoresce within 30-40 seconds, exhibiting a green hue. The surgeon will perform the pulmonary resection and the resected 'dark' lung segment will be immediately evaluated by a pathologist, depending on the pathologist findings the operation may be concluded or the patient will receive a pulmonary lobectomy.

Trial Locations (1)

L8N 4A6

RECRUITING

St. Joseph's Healthcare Hamilton, Hamilton

All Listed Sponsors
lead

St. Joseph's Healthcare Hamilton

OTHER