Dissociating Components of Anhedonia: A Pilot fMRI Study

NACompletedINTERVENTIONAL
Enrollment

46

Participants

Timeline

Start Date

February 29, 2016

Primary Completion Date

May 8, 2018

Study Completion Date

May 8, 2018

Conditions
Anhedonia
Interventions
OTHER

Functional Magnetic Resonance Imaging

"Both groups will have the fMRI performed once. The fMRI will be use to to dissociate activity associated with both reward wanting and reward liking using the EEfRT. Learning more about the brain basis of components of anhedonia in both young and older adults is important in the context of previous research showing that risk-taking behavior and reward sensitivity changes with age, enhancing the knowledge of anhedonia."

OTHER

Effort-Expenditure for Rewards Task

"Both groups with have the EEfRT performed once. The EEfRT is an effort-based decision-making task that measures reward wanting, in contrast to commonly used anhedonia questionnaires, which focus on reward liking. This novel task may provide a useful measure of components of anhedonia in older adults and in different patient populations."

Trial Locations (1)

32610

University of Florida, Gainesville

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

University of Florida

OTHER

NCT02569034 - Dissociating Components of Anhedonia: A Pilot fMRI Study | Biotech Hunter | Biotech Hunter