Pharmacokinetic and Mosquito-Lethal Effects of Ivermectin (IVM), Primaquine (PQ), Dihydroartemisinin-Piperaquine (DHA-PQP) and Albendazole (ABZ) in Healthy Subjects

PHASE1CompletedINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

October 31, 2015

Primary Completion Date

December 31, 2016

Study Completion Date

December 31, 2016

Conditions
Drug CombinationPharmacokineticsHealthy
Interventions
DRUG

IVM, IVM and PQ, IVM and DHA-PQP, IVM and DHA-PQP and PQ

Regimen 1: IVM; Regimen 2: IVM and PQ; Regimen 3: IVM and DHA-PQP; Regimen 4: IVM and DHA-PQP and PQ;

DRUG

PQ and DHA-PQP and PQ

Regimen 5: PQ; Regimen 7: DHA-PQP and PQ

DRUG

DHA-PQP

Regimen 6: DHA-PQP

Trial Locations (1)

10400

Faculty of Tropical Medicine, Bangkok

All Listed Sponsors
collaborator

Mahidol University

OTHER

collaborator

Mahidol Oxford Tropical Medicine Research Unit

OTHER

lead

University of Oxford

OTHER

NCT02568098 - Pharmacokinetic and Mosquito-Lethal Effects of Ivermectin (IVM), Primaquine (PQ), Dihydroartemisinin-Piperaquine (DHA-PQP) and Albendazole (ABZ) in Healthy Subjects | Biotech Hunter | Biotech Hunter