NCT02565498View on ClinicalTrials.gov

Preoperative vs Postoperative IMRT for Extremity/Truncal STS

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

210

Participants

Timeline

Start Date

June 30, 2016

Primary Completion Date

October 31, 2024

Study Completion Date

May 31, 2029

Conditions
Adult Soft Tissue Sarcoma
Interventions
RADIATION

Preoperative intensity modulated radiation therapy

50 Gy delivered in 25 fractions 4-6 weeks prior to surgical excision

RADIATION

Postoperative intensity modulated radiation therapy

Surgery followed by 50 Gy delivered in 25 fractions within 6 weeks of surgery for patients with negative margins; for patients with positive margins a boost of 16 Gy in 8 fractions will be added.

Trial Locations (8)

44195

Cleveland Clinic Taussig Cancer Institute, Cleveland

02215

Dana Farber Cancer Institute, Boston

97239-3098

Oregon Health & Science University, Portland

Unknown

Cliniques Universitaires Saint-Luc, Brussels

K1H 8L6

The Ottawa Hospital Cancer Centre, Ottawa

M5G 1X5

Mount Sinai Hospital, Toronto

M5G 2M9

Princess Margaret Cancer Centre, Toronto

H1T 2M4

Hopital Maisonneuve-Rosemont, Montreal

All Listed Sponsors
collaborator

Princess Margaret Hospital, Canada

OTHER

lead

Mount Sinai Hospital, Canada

OTHER