FDA Approved Medication to Reduce Binge Eating and/or Purging

PHASE1CompletedINTERVENTIONAL
Enrollment

22

Participants

Timeline

Start Date

October 30, 2015

Primary Completion Date

February 23, 2017

Study Completion Date

April 15, 2017

Conditions
Binge Eating DisorderBulimia Nervosa
Interventions
DRUG

Phentermine/Topiramate-First

Patients randomly assigned to this Arm will have a 4 week ramp up period (in which doses will be increased, as tolerated, starting from 3.75 mg/23 mg, 7.5 mg/46 mg ,11.25 mg/69 mg , 15 mg/92 mg taken once daily in the morning. For the final 8 weeks, participants will take the 15mg/92 mg (or highest dose tolerated). Then will have a 2 week washout followed by a crossover to 12 weeks of control medication/ placebo.

DRUG

Placebo

Patients randomly assigned to this Arm will have begin with 12 weeks of placebo followed by a 2 week washout. They will then crossover to Qsymia and receive a 4 week ramp up period (in which doses will be increased, as tolerated, starting from 3.75 mg/23 mg, 7.5 mg/46 mg ,11.25 mg/69 mg , 15 mg/92 mg taken once daily in the morning. For the final 8 weeks, participants will take the 15mg/92 mg (or highest dose tolerated).

Trial Locations (1)

94305

Stanford School of Medicine, Psychiatry and Behavioral Sciences, Stanford

All Listed Sponsors
lead

Stanford University

OTHER

NCT02553824 - FDA Approved Medication to Reduce Binge Eating and/or Purging | Biotech Hunter | Biotech Hunter