Remote Ischemic Limb Preconditioning In Healthy Volunteers

NACompletedINTERVENTIONAL
Enrollment

17

Participants

Timeline

Start Date

October 31, 2015

Primary Completion Date

June 1, 2021

Study Completion Date

June 3, 2021

Conditions
Cerebrovascular DiseaseStroke
Interventions
PROCEDURE

4x 5min Limb Preconditioning

A blood pressure cuff is placed over the upper thigh of the participant(s) and inflated to 30 millimeters of mercury (mmHg) above systolic blood pressure. The loss of pedal pulses is confirmed by palpation. The cuff remains inflated for 5min and is followed by 5 minutes of reperfusion/rest. This will be repeated 4 times.

PROCEDURE

3x 10min Limb Preconditioning

A blood pressure cuff is placed over the upper thigh of the participant(s) and inflated to 30 mmHg above systolic blood pressure. The loss of pedal pulses is confirmed by palpation. The cuff remains inflated for 10min and is followed by 5 minutes of reperfusion/rest. This will be repeated 3 times.

PROCEDURE

3x 10min Sham Preconditioning

A blood pressure cuff is placed over the upper thigh of the participant(s) and inflated to 40 mmHg, sufficient to apply pressure but not affect blood flow. The presence of pedal pulses is confirmed by palpation. The cuff remains inflated for 10min and is followed by 5 minutes of rest. This will be repeated 3 times.

Trial Locations (1)

33136

University of Miami, Miami

All Listed Sponsors
lead

University of Miami

OTHER

NCT02553655 - Remote Ischemic Limb Preconditioning In Healthy Volunteers | Biotech Hunter | Biotech Hunter