34
Participants
Start Date
September 11, 2015
Primary Completion Date
June 19, 2020
Study Completion Date
May 13, 2021
Chemosensitivity Assay
Lab test in which leukemia cells obtained from blood or bone marrow are tested for sensitivity to 115 drugs individually and in certain combinations
Cytology Specimen Collection Procedure
Undergo blood or bone marrow collection
Gene Expression Analysis
Analysis of leukemia cell genes to identify possible drug targets
Genetic Variation Analysis
Analysis of leukemia cell genes to identify possible drug targets
In Vitro Sensitivity-Directed Chemotherapy
"Receive personalized chemotherapy with one or more of the following drugs:~Afatinib Arsenic trioxide Axitinib Azacitidine Bexarotene Bortezomib Bosutinib Busulfan Cabazitaxel Cabozantinib Carfilzomib Ceritinib Cladribine Clofarabine Crizotinib Cytarabine HCl Dabrafenib Dasatinib Daunorubicin HCl Decitabine Erlotinib Etoposide Everolimus Fludarabine Gefitinib Gemcitabine HCl Hydroxyurea Imatinib Irinotecan Lapatinib Lomustine Melphalan Mercaptopurine Methotrexate Mitoxantrone Nelarabine Nilotinib Paclitaxel Pazopanib Pentostatin Ponatinib Pralatrexate Rapamycin Regorafenib Romidepsin Ruxolitinib Sorafenib Sunitinib Temsirolimus Thioguanine Topotecan HCl Trametinib Tretinoin"
Fred Hutch/University of Washington Cancer Consortium, Seattle
National Cancer Institute (NCI)
NIH
University of Washington
OTHER