Association Between High Faecal Calprotectin, Increased Intestinal Permeability and Visceral Hypersensitivity in IBS-D Patients

NACompletedINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

May 20, 2016

Primary Completion Date

May 20, 2021

Study Completion Date

May 20, 2021

Conditions
Irritable Bowel Syndrome
Interventions
PROCEDURE

Colonoscopy with eleven biopsies in the left colon to assess intestinal permeability

Eleven colonic biopsies are taken in the left colon during colonoscopy. Intestinal permeability is assessed by western blot, qPCR and immunofluorescence for claudin, occludin and ZO-1.

Trial Locations (1)

76031

Rouen University Hospital, Rouen

All Listed Sponsors
collaborator

Société Nationale Française de Gastroentérologie

OTHER

lead

University Hospital, Rouen

OTHER

NCT02550704 - Association Between High Faecal Calprotectin, Increased Intestinal Permeability and Visceral Hypersensitivity in IBS-D Patients | Biotech Hunter | Biotech Hunter