The Bowel CLEAnsing: A National Initiative

PHASE4CompletedINTERVENTIONAL
Enrollment

3,476

Participants

Timeline

Start Date

March 31, 2016

Primary Completion Date

September 30, 2018

Study Completion Date

September 30, 2018

Conditions
Subjets Requiring a Colonoscopy
Interventions
DRUG

High volume PEG split-dose

Colyte® or PegLyte® will be provided to the subject who will be asked to drink 2L of the preparation starting at 7:00 PM the day before the procedure at a rate of 240 mL every 10 minutes until completed. The second dose of 2L of preparation will be taken the morning of the colonoscopy starting 4-5 hours prior to the planned procedural time at a rate of 240 mL every 10 minutes until completed.

DRUG

Low volume PEG split-dose

Bi-PegLyte® will be provided to the subject who will be asked to ingest 3 tabs of Bisacodyl 5 mg (total 15 mg) at 2:00 PM the day before the procedure. After the first bowel movement, or if there is no bowel movement within 6 hours of taking the Bisacodyl tablets, the subject will be asked to drink 1L of the solution at a rate of 240 mL every 10 minutes until the solution is completed. The second dose of 1L of preparation will be taken the morning of the colonoscopy starting 4-5 hours prior to the procedure at a rate of 240 mL every 10 minutes. Use of antacids will not be permitted within one hour of taking bisacodyl.

DRUG

High volume PEG non split, day before

Colyte® or PegLyte® will be provided to the subject who will be asked to drink 4L of preparation starting at 6:00 PM the day before the procedure, at a rate of 240 mL every 10 minutes until completed.

DRUG

Low volume PEG non split, same day

Bi-PegLyte® will be provided to the subject, who will be asked to ingest 3 tabs of Bisacodyl 5 mg (total 15 mg) at 2:00 PM the day before the procedure and will drink 2L of preparation the morning of the colonoscopy starting 4 hours prior to the procedure at a rate of 240 mL every 10 minutes, until completed. Use of antacids will not be permitted within one hour of taking Bisacodyl.

OTHER

Clear liquid diet

OTHER

Low residue diet

OTHER

Early colonoscopy (stratified)

"Early appointments: 7:30 AM to 10h30 AM"

OTHER

Later colonoscopy (stratified)

"Later appointments: 10:30 AM to 4:30 PM."

Trial Locations (10)

T2N 4Z6

Forzani & MacPhail Colon Cancer Screening Centre, Calgary

T6G 2X8

University of Alberta Hospital, Edmonton

V6Z 2K5

St. Paul's Hospital, Vancouver

R2H 2A6

Health Sciences center and St. Boniface Hospital, Winnipeg

B3H 2Y9

QEII HSC, Halifax

N6A 5W9

Western University, London

K1H 1A2

The Ottawa Hospital, Ottawa

H2W 2J3

CHUM, Montreal

H3G 1A4

McGill University Health Centre, Montreal

G1S 4L8

Hôpital St-Sacrement, CHU de Québec-Université Laval, Québec

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Pendopharm

INDUSTRY

lead

Alan Barkun

OTHER

NCT02547571 - The Bowel CLEAnsing: A National Initiative | Biotech Hunter | Biotech Hunter