Assessment of Corneal Graft Attachment in Patients With Fuchs Endothelial Corneal Dystrophy Following DMEK Using Ultra-high Resolution OCT

NACompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

November 15, 2017

Primary Completion Date

March 15, 2022

Study Completion Date

March 15, 2022

Conditions
Fuchs' Endothelial Dystrophy
Interventions
DEVICE

Ultrahigh resolution Spectral Domain OCT

"The area of graft detachment will be measured by a customized ultra high-resolution OCT for the cornea.~A spectrometer based ultrahigh resolution Spectral Domain OCT (SDOCT) system operating at 800 nm for the anterior chamber will be employed in the present study. The spectrum of the Ti:Sapphire laser light source is centered at 800 nm. With a full width at half maximum bandwidth of 170 nm, the axial resolution is 1.3 μm in the cornea. The transverse resolution of the employed OCT system is 21 μm at the front surface of the cornea. For measurement, patients will place their head in a modified slit lamp head rest. During the measurement period, patients will be asked to look straight forward onto an internal fixation target and to avoid blinking. Different scattering patterns, e.g. raster, circular and spiral scans will be employed."

Trial Locations (2)

1090

Medical University Vienna, Department of Clinical Pharmacology, Vienna

1140

Vienna Institute for Research in Ocular Surgery (VIROS), Vienna

All Listed Sponsors
lead

Medical University of Vienna

OTHER

NCT02542644 - Assessment of Corneal Graft Attachment in Patients With Fuchs Endothelial Corneal Dystrophy Following DMEK Using Ultra-high Resolution OCT | Biotech Hunter | Biotech Hunter