Strengthening Instrumental Extinction to Prevent Smoking Relapse (VLNCCue)

NACompletedINTERVENTIONAL
Enrollment

87

Participants

Timeline

Start Date

October 8, 2015

Primary Completion Date

September 8, 2017

Study Completion Date

September 8, 2017

Conditions
Cigarette Smoking
Interventions
DRUG

Nicotine Patch

Both groups will receive nicotine patches (21 mg/d if smoking ≥10 cigs/d or 14 mg/d if smoking \<10 cigs/d) to wear for 3 weeks prior to the quit date. After the quit date, both groups will wear the nicotine patch for 10 weeks. Participants that smoked ≥10 cigs/d will wear a 21 mg/d patch for 6 weeks, a 14 mg/d patch for 2 weeks, and a 7 mg/d patch for 2 weeks. Participants that smoked \<10 cigs/d will wear a 14 mg/d patch for 6 weeks, then step down to a 7 mg/d patch for 4 weeks.

DRUG

SPECTRUM Nicotine Research Cigarettes (0.07 mg)

For 3 weeks prior to their quit day, participants will switch to smoking SPECTRUM Nicotine Research Cigarettes instead of their usual brand.

BEHAVIORAL

MCE+

During the 3-week, pre-quit period, participants will undergo six, 60 minute sessions during which they will view smoking-related environments and smoke their assigned cigarettes.

BEHAVIORAL

MCE-

During the 3-week, pre-quit period, participants will undergo six, 60 minute sessions during which they will view nature environments and smoke their assigned cigarettes.

Trial Locations (1)

27705

Duke Medical Center, Durham

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

Francis McClernon, Ph.D.

OTHER

NCT02538042 - Strengthening Instrumental Extinction to Prevent Smoking Relapse (VLNCCue) | Biotech Hunter | Biotech Hunter