Development Of Neuroimaging Methods To Assess The Neurobiology Of Addiction

1H MR spectroscopy to assess brain metabolites.

Three fMRI sessions to assess test-retest reliability of functional connectivity (FC) measures at rest and during task performance.

Electroencephalography or electrooculography (EEG/ EOG) sessions to record electrical activity of the brain or measure corneo-retinal standing potentials.

To be used in the context of fMRI to study blood-oxygenation-level- dependent responses in the brain to sensory stimulation.

To be used in conjunction with pupillometry in the context of fMRI to study blood-oxygenation-level-dependent responses to selective neurostimulation of pain fibers.

High spatial MRI and diffusion tensor imaging (DTI) to assess brain morphology and structural connectivity.