Efficacy of Acetaminophen in Posterior Fossa Surgery

PHASE2WithdrawnINTERVENTIONAL
0
Timeline

Start Date

November 30, 2015

Primary Completion Date

June 30, 2018

Study Completion Date

October 31, 2018

Conditions
Arnold-Chiari MalformationPosterior Fossa Tumors
Interventions
DRUG

IV acetaminophen

IV acetaminophen 15 mg/kg (1.5 mL/kg) IV loading dose prior to incision, followed by a 15 mg/kg (1.5 mL/kg) dose given every 6 hours for the first 24 hours after surgery (total of 4 doses postoperatively)

DRUG

normal saline

normal saline 1.5 mL/kg IV loading dose prior to incision, followed by a 1.5 mL/kg dose given every 6 hours for the first 24 hours after surgery (total of 4 doses postoperatively)

Trial Locations (1)

20010

Children's National Health System, Washington D.C.

All Listed Sponsors
lead

Children's National Research Institute

OTHER