Study of the Reversibility of Glucose Intolerance Caused by Chronic Aspartame Consumption

NACompletedINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

August 31, 2015

Primary Completion Date

June 25, 2019

Study Completion Date

June 25, 2019

Conditions
Glucose Metabolism Disorder
Interventions
OTHER

Oral glucose tolerance test (OGTT)

OGTT will be conducted following a ten (10) hour fast on Screening Visit 2 (Screening Visit 2 may be conducted between Day -42 to Day 1).

OTHER

Diet soda containing aspartame only

7 days of 36 oz diet soda po daily (Week 1), followed by 21 days washout (Weeks 2-4), and 7 days rechallenge (Week 5); Prudent metabolic diet; Oral glucose tolerance test (OGTT) on days (+/-2) 3, 7, 10, 14, 21, 28, 31, 35

Trial Locations (1)

10065

The Rockefeller University, New York

All Listed Sponsors
lead

Rockefeller University

OTHER

NCT02520258 - Study of the Reversibility of Glucose Intolerance Caused by Chronic Aspartame Consumption | Biotech Hunter | Biotech Hunter