NCT02520128 - A Study of IMRT in Primary Bone and Soft Tissue Sarcoma | Biotech Hunter

Enrollment

191

Participants

Timeline

Start Date

March 31, 2016

Primary Completion Date

June 30, 2020

Study Completion Date

June 30, 2020

Conditions

Soft Tissue Sarcoma, AdultEwing SarcomaBone SarcomaChordoma

Interventions

RADIATION

Intensity modulated radiotherapy (IMRT)

Intensity modulated radiotherapy (IMRT) is an advanced radiotherapy technique that is able to deliver a highly conformal dose to a target with improved sparing of the surrounding normal tissues from moderate to high radiation doses. IMRT is likely to be of particular benefit for tumours that have complex shapes, or those in close proximity to sensitive normal tissues and critical organs. Reducing the dose to normal tissues may in turn reduce the acute and late side effects of treatment. IMRT can be delivered from multiple fixed beam angles or through rotational arc applications such as volumetric modulated arc therapy (VMAT) and tomotherapy. The radiotherapy is delivered using multiple small beams (beamlets) of non-uniform intensity.

Trial Locations (28)

Unknown

St Luke's Hospital, Dublin

Clatterbridge Cancer Centre, Bebington

Belfast City Hospital, Belfast

Queen Elizabeth Hospital, Birmingham

Bristol Haematology and Oncology Centre, Bristol

Adenbrookes' Hospital, Cambridge

Cheltenham Hospital, Cheltenham

University Hospital Coventry, Coventry

Western General Hospital, Edinburgh

St James' Institute of Oncology, Leeds

Leicester Royal Infirmary, Leicester

The Christie Hospital, Manchester

Northern Centre for Cancer Care, Newcastle

Northampton General Hospital, Northampton

Nottingham City Hospital, Nottingham

Churchill Hospital, Oxford

Derriford Hospital, Plymouth

Royal Preston Hospital, Preston

The Royal Marsden NHS Foundation Trust, Sutton

Singleton Hospital, Swansea

CF5 6SH

Velindre Hospital, Cardiff

DE22 3NE

Royal Derby Hospital, Derby

EX2 5DW

Royal Devon & Exeter Foundation Trust, Exeter

G12 0YN

Beatson West of Scotland Cancer Centre, Glasgow

NW1 2PG

University College London Hospitals, London

NR4 7UY

Norfolk and Norwich University Hospital, Norwich

S10 2SJ

Weston Park Hospital, Sheffield

SO16 6YD

Southampton General Hospital, Southampton