Bioavailability of Paracetamol, Amoxicillin and Talinolol Before, Immediately and One Year After Gastric Bypass Operation

Administration of 5 ml Paracetamol Saft Hexal (= 200 mg paracetamol)

Administration of 5 ml Amoxypen® 250 mg Saft (= 250 mg amoxicillin)

Administration of 1 tablet Cordanum® 50 (= 50 mg talinolol) dissolved with 40 ml tap water

Gastroduodenoscopy with biopsy of the lower duodenum before the first pharmacokinetic study period

Gastrojejunoscopy with biopsy of the jejunum about one year after proximal Roux-en-Y gastric bypass

sampling of a tissue specimen from the jejunum during the operation