14
Participants
Start Date
November 30, 2015
Primary Completion Date
May 29, 2020
Study Completion Date
May 29, 2021
Ceritinib
Patients will receive ceritinib at a dose of 750 mg (150 mg capsules times 5 capsules once a day) for 10 weeks. Patient will stop taking Ceritinib 72 hours before SABR radiation. The patient may start taking Ceritinib again 72 hours after radiation is complete. Patient will continue to take certinib for up to 8 months.
Stereotactic ablative body radiation
Patients will receive study drug for 10 weeks. They could get 1, 3 ,or 5 treatments on consecutive days with 18 hours between each treatment or every other day (doctor's determination).
UT Southwestern Medical Center, Dallas
Collaborators (1)
Novartis Pharmaceuticals
INDUSTRY
University of Texas Southwestern Medical Center
OTHER