TIcagrelor in Rotational Atherectomy to Reduce TROPonin Enhancement

PHASE4CompletedINTERVENTIONAL
Enrollment

180

Participants

Timeline

Start Date

November 30, 2015

Primary Completion Date

May 24, 2018

Study Completion Date

May 30, 2018

Conditions
Atherosclerosis
Interventions
DRUG

ticagrelor

"Ticagrelor will be administered orally, according to the following scheme:~* 180 mg the evening preceding (and at least 6 hours before) rotational atherectomy (Day -1),~* 90 mg the following morning (D Day before rotational atherectomy and angioplasty),~* 90 mg the following evening (D Day after rotational atherectomy and angioplasty),~* 90 mg twice daily the day after the procedure of rotational atherectomy and angioplasty (Day +1)."

DRUG

clopidogrel

"Clopidogrel will be administered orally, according to the following scheme:~* 300 mg the evening preceding (and at least 6 hours before) rotational atherectomy (Day -1),~* 75 mg the following morning (D Day before rotational atherectomy and angioplasty),~* 0 mg the following evening (D Day after rotational atherectomy and angioplasty),~* 75 mg once daily the day after the procedure of rotational atherectomy and angioplasty (Day +1)."

Trial Locations (4)

30000

University Hospital, Nîmes

31000

Clinique Pasteur, Toulouse

31059

Fédération de Cardiologie CHU TOULOUSE, Toulouse

69000

Hospices civils de Lyon, Lyon

All Listed Sponsors
lead

University Hospital, Toulouse

OTHER

NCT02505399 - TIcagrelor in Rotational Atherectomy to Reduce TROPonin Enhancement | Biotech Hunter | Biotech Hunter