Efficacy of HBV Vaccine in Consolidation of Nucleos(t)Ide Analogues Therapy

PHASE4CompletedINTERVENTIONAL
Enrollment

116

Participants

Timeline

Start Date

May 1, 2015

Primary Completion Date

December 21, 2018

Study Completion Date

December 21, 2018

Conditions
Chronic Hepatitis B
Interventions
DRUG

Engerix-B

The case group will receive 5 Engerix-B injections during the last 6 months of a 3-year NA therapy.

DRUG

Tenofovir

Both case and control will receive 300 mg Tenofovir for at least 3 years

DRUG

Entecavir

Both case and control will receive 0.5 mg entecavir therapy for at least 3 years

Trial Locations (1)

10507

Chang Gung Memorial Hospital, Taipei

All Listed Sponsors
lead

Chang Gung Memorial Hospital

OTHER

NCT02505009 - Efficacy of HBV Vaccine in Consolidation of Nucleos(t)Ide Analogues Therapy | Biotech Hunter | Biotech Hunter