Core Temperature Variations During Midazolam vs Propofol Sedation for Neuraxial Anesthesia

NACompletedINTERVENTIONAL
Enrollment

27

Participants

Timeline

Start Date

July 31, 2015

Primary Completion Date

March 31, 2016

Study Completion Date

March 31, 2016

Conditions
Body Temperature ChangesAnesthesia
Interventions
DRUG

Midazolam

The investigators will administer 0,05mg/kg of midazolam, being 2/3 administered before the neuraxial block and 1/3 after.

DRUG

Propofol

The investigators will administer 0,033mg/kg of midazolam before the neuraxial block, and immediately after installation of the block the investigators will start a propofol TCI pump (Schnider model) with an effect concentration set at 1mcg/mL. This pump will be turned off at the end of the surgery.

DRUG

Standard

The investigators will administer to every patient: cefazolin 2g iv bolus, ketorolac 30 mg iv bolus, pantoprazole 40 mg iv bolus, paracetamol 1g iv perfusion (initiated 30 minutes before the end of surgery).

DEVICE

SpotOn

Central temperature will be monitored with the SpotOnTM3MTM device from entering till leaving the operating room, through a sensor placed in the patient's forehead

Trial Locations (1)

1500-650

Hospital da Luz, Lisbon

All Listed Sponsors
lead

Hospital da Luz, Portugal

OTHER

NCT02502877 - Core Temperature Variations During Midazolam vs Propofol Sedation for Neuraxial Anesthesia | Biotech Hunter | Biotech Hunter