NCT02500004 - Brown Adipose Tissue Activity and Energy Metabolism in Cachexia | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

June 30, 2015

Primary Completion Date

July 31, 2018

Study Completion Date

July 31, 2018

Conditions

CachexiaNeoplasmsPulmonary Disease, Chronic ObstructivePancreatic Neoplasms

Interventions

RADIATION

18F-FDG PET-MRI-imaging

BAT activity: 18F-FDG PET-MRI-imaging.

RADIATION

DXA scanning

Body composition: DXA scanning, D2O and MRI.

PROCEDURE

Abdominal subcutaneous adipose tissue biopsy

Inflammatory and metabolic profile of adipose tissue: abdominal subcutaneous adipose tissue biopsy.

PROCEDURE

Blood sampling

Systemic inflammatory profile: blood sampling.

OTHER

Indirect calorimetry

Resting metabolic rate: indirect calorimetry.

DEVICE

Accelerometry

Physical activity level: accelerometry.

OTHER

Double-labeled water

Body composition: DXA scanning, D2O and MRI. Total daily energy expenditure: double-labeled water.

Trial Locations (1)

Maastricht UMC+, Maastricht

All Listed Sponsors

lead

Maastricht University Medical Center

OTHER