A Study of DSP-7888 Dosing Emulsion in Adult Patients With Advanced Malignancies

PHASE1CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

November 30, 2015

Primary Completion Date

August 31, 2018

Study Completion Date

September 30, 2018

Conditions
Acute Myeloid LeukemiaMyelodysplastic SyndromesGlioblastoma MultiformeMelanomaNon-Small Cell Lung CancerOvarian CancerPancreatic CancerSarcomaRenal Cell Carcinoma
Interventions
DRUG

DSP-7888 Dosing Emulsion

"Dose escalation cohort: Patients will be administered escalating doses of DSP-7888 Dosing Emulsion intradermally or subcutaneously in accordance with the following regimen: once weekly for four weeks during the Induction Phase, once every 7 to 14 days for 6 weeks during the Consolidation Phase, and once every 14 to 28 days until a discontinuation criterion is met during the Maintenance Phase.~MDS cohort 1: Patients will be intradermally administered of DSP-7888 at 10.5 mg every week for 4 weeks, every 2 weeks until Week 24, and then every 4 weeks.~MDS cohort 2: Patients will be intradermally administered of DSP-7888 at 10.5 mg every 2 weeks until Week 24, and then every 4 weeks."

Trial Locations (8)

22031

USOR - VA Cancer Specialists, Fairfax

23502

USOR - VA Oncology Associates, Norfolk

30322

Emory University Winship Cancer Institute, Atlanta

47905

Horizon Oncology Research, Lafayette

75246

USOR -TX Oncology Dallas, Dallas

75702

USOR - TX Oncology Tyler, Tyler

78705

USOR - TX Oncology Austin, Austin

80218

USOR - Rocky Mountain Cancer Center, Denver

All Listed Sponsors
lead

Sumitomo Pharma America, Inc.

INDUSTRY

NCT02498665 - A Study of DSP-7888 Dosing Emulsion in Adult Patients With Advanced Malignancies | Biotech Hunter | Biotech Hunter