A Study Comparing the Efficacy, Safety and Tolerability of Oral Dydrogesterone 30 mg Daily Versus Crinone 8% Intravaginal Progesterone Gel 90 mg Daily for Luteal Support in In-Vitro Fertilization (LOTUS II)

PHASE3CompletedINTERVENTIONAL
Enrollment

1,034

Participants

Timeline

Start Date

July 31, 2015

Primary Completion Date

May 31, 2017

Study Completion Date

May 31, 2017

Conditions
Female Infertility
Interventions
DRUG

Dydrogesterone 30 mg

Oral Dydrogesterone 10 mg tablets tid

DRUG

intravaginal progesterone gel 90 mg

Trial Locations (40)

1090

Universitair Ziekenhuis Brussel, Jette

1200

Univerité Catholique de Louvain, Cliniques universitaires Saint-Luc, Brussels

2217

IVF Australia - St George Private HospitalIVF Australia - St George Private Hospital, Kogarah

3002

Melbourne IVF, East Melbourne

9000

Algemeen Ziekenhuis Jan Palfijn Gent, Ghent

UZ Gent, Ghent

14050

Fertility Center Berlin, Berlin

23538

Universitäres Kinderwunschzentrum Lübeck, Lübeck

33619

Bielefeld Fertility Center, Bielefeld

44135

Kinderwunschzentrum Dortmund, Dortmund

50200

Maharaj Nakorn Chiang Mai Hospital, Chiang Mai

58022

"Medical Centre of Infertility Treatment Clinic of Professor Yuzko", Chernivtsi

90110

Songklanagarind Hospital, Bangkok

100044

Peking University People's Hospital, Beijing

110029

All India Institute of Medical Sciences, Delhi

110057

Max Hospital, Delhi

117997

Scientific Research Center of Obstetrics, Gynecology and Perinatology n. a. Ac. V. I. Kulakova, Moscow

119192

"CJSC Nasledniki", Moscow

169608

Singapore General Hospital, Singapore

193174

"Saint-Petersburg State Budgetary Healtcare Institution Maternity Hospital # 17", Saint Petersburg

210029

The First Affiliated Hospital of Nanjing Medical University, Nanjing

226005

Ajanta Research Center, Ajanta Hospital and IVF center, Lucknow

230022

The First Affiliate Hospital of Anhui Medical University, Hefei

410008

Reproductive & Genetic Hospital of Citic -Xiangya, Changsha

411002

Inamdar Multispecialty Hospital, Pune

411006

Shree Hospital and Diagnostic Centre, Pune

430030

Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan

431005

United CIIGMA Hospital, Aurangabad

450052

First Affiliated Hospital of Zhengzhou University, Zhengzhou

510120

Sun Yat-Sen Memorial Hsopiatl, Sun Yat-Sen University, Guangzhou

510655

The Sixth Hospital of Sun Yat-Sen University, Guangzhou

560001

MILANN (Bangalore Assisted Conception Center), Bangalore

560076

Apollo Hospitals - Bangalore, Bangalore

610041

West China Second University Hospital, Chengdu

620043

"CJSC Center of Family Medicine", Yekaterinburg

700014

Institute of Reproductive Medicine, Kolkata

Unknown

Queen Mary Hospital, Hong Kong

03037

"NADIYA Clinic", Kiev

04107

The Institute for Reproductive Medicine in Ukraine, Kiev

0411

"Mother and Child clinic", Kiev

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

PRA Health Sciences

INDUSTRY

collaborator

Datamap

INDUSTRY

lead

Abbott

INDUSTRY