Effectiveness Study of Nivolumab Compared to Chemotherapy in Patients With Relapsed Small-cell Lung Cancer

PHASE3CompletedINTERVENTIONAL
Enrollment

569

Participants

Timeline

Start Date

September 14, 2015

Primary Completion Date

August 17, 2018

Study Completion Date

August 30, 2022

Conditions
Lung Cancer
Interventions
DRUG

Nivolumab

DRUG

Topotecan

DRUG

Amrubicin

Trial Locations (151)

0

Local Institution - 0025, Recoleta

Local Institution - 0198, Guangzhou

Local Institution - 0138, Kfar Saba

404

Local Institution - 0143, Taichung

1011

Local Institution - 0133, Lausanne

1083

Local Institution - 0112, Budapest

1090

Local Institution - 0086, Vienna

1121

Local Institution - 0110, Budapest

Local Institution - 0150, Budapest

1200

Local Institution - 0013, Brussels

2100

Local Institution - 0106, Copenhagen

2298

Local Institution - 0102, Waratah

2650

Local Institution - 0012, Edegem

2730

Local Institution - 0098, Herlev

3000

Local Institution - 0011, Leuven

4031

Local Institution - 0104, Basel

4032

Local Institution - 0030, Brisbane

4600

Local Institution - 0084, Wels

5000

Local Institution - 0100, Odense

5021

Local Institution - 0096, Bergen

5037

Local Institution - 0103, Kurralta Park

5112

Local Institution - 0031, Elizabeth Vale

5530

Local Institution - 0010, Yvoir

6150

Local Institution - 0028, Perth

Local Institution - 0027, Murdoch

8036

Local Institution - 0085, Graz

8091

Local Institution - 0156, Zurich

8401

Local Institution - 0109, Winterthur

11527

Local Institution - 0062, Athens

13100

Local Institution - 0166, Safed

13125

Local Institution - 0055, Berlin

13790

Local Institution - 0173, Johnson City

14059

Local Institution - 0066, Prague

16247

Local Institution - 0145, Suwon

17604

Local Institution - 0057, Lancaster

18015

Local Institution - 0002, Bethlehem

20052

Local Institution - 0080, Monza

20133

Local Institution - 0078, Milan

21075

Local Institution - 0059, Hamburg

22927

Local Institution - 0021, Großhansdorf

27710

Local Institution - 0001, Durham

28034

Local Institution - 0004, Madrid

28050

Local Institution - 0003, Madrid

28644

Local Institution - 0146, Cheongju-si

29200

Local Institution - 0134, Brest

30322

Local Institution - 0018, Atlanta

37203

Local Institution - 0089, Nashville

37232

Local Institution - 0009, Nashville

40139

Local Institution - 0081, Bologna

41009

Local Institution - 0008, Seville

44106

Local Institution - 0090, Cleveland

45122

Local Institution - 0047, Essen

46026

Local Institution - 0007, Valencia

46145

Local Institution - 0054, Oberhausen

47014

Local Institution - 0077, Meldola

47923

Local Institution - 0107, Rimini

50937

Local Institution - 0023, Cologne

51100

Local Institution - 0132, Reims

52621

Local Institution - 0136, Ramat Gan

55100

Local Institution - 0108, Lucca

56429

Local Institution - 0097, Thessaloniki

57100

Local Institution - 0073, Livorno

59037

Local Institution - 0116, Lille

60590

Local Institution - 0071, Frankfurt am Main

63110

Local Institution - 0056, St Louis

68506

Local Institution - 0088, Lincoln

69126

Local Institution - 0020, Heidelberg

70839

Local Institution - 0019, Gerlingen

71110

Local Institution - 0063, Heraklion

72205

Local Institution - 0065, Little Rock

74374

Local Institution - 0131, Pringy

75014

Local Institution - 0118, Paris

81925

Local Institution - 0022, München

83056

Local Institution - 0117, Toulon

84101

Local Institution - 0139, Beersheba

87509

Local Institution - 0046, Immenstadt im Allgäu

93053

Local Institution - 0064, Regensburg

96049

Local Institution - 0061, Bamberg

99336

Local Institution - 0070, Kennewick

100001

Local Institution - 0200, Beijing

100021

Local Institution - 0199, Beijing

100032

Local Institution - 0188, Beijing

100071

Local Institution - 0201, Beijing

101149

Local Institution - 0190, Beijing

115478

Local Institution - 0122, Moscow

130012

Local Institution - 0187, Changchun

194291

Local Institution - 0119, Saint Petersburg

197758

Local Institution - 0126, Saint Petersburg

200025

Local Institution - 0181, Shanghai

200030

Local Institution - 0192, Shanghai

200032

Local Institution - 0185, Shanghai

200347

Local Institution - 0114, Craiova

210000

Local Institution - 0194, Nanjing

300239

Local Institution - 0149, Timisoara, Timis

310016

Local Institution - 0182, Hangzhou

310022

Local Institution - 0183, Hangzhou

390011

Local Institution - 0121, Ryazan

400015

Local Institution - 0113, Romania

450008

Local Institution - 0189, Zhengzhou

510080

Local Institution - 0197, Guanzhou

710038

Local Institution - 0186, Xi'an

830011

Local Institution - 0202, Ürümqi

1040045

Local Institution - 0170, Chuo-ku

1138431

Local Institution - 0176, Bunkyo-ku

4648681

Local Institution - 0159, Nagoya

5340021

Local Institution - 0165, Osaka

5418567

Local Institution - 0174, Chuo-ku

5731191

Local Institution - 0175, Hirakata-shi

5838588

Local Institution - 0171, Habikino-shi

6500047

Local Institution - 0163, Kobe

6738558

Local Institution - 0168, Akashi-shi

7910280

Local Institution - 0155, Matsuyama

9811293

Local Institution - 0164, Natori-shi

06520

Local Institution - 0024, New Haven

19111-2412

Local Institution - 0053, Philadelphia

98700-000

Local Institution - 0095, Ijuí

90610-000

Local Institution - 0094, Porto Alegre

14784-400

Local Institution - 0093, Barretos

01321-001

Local Institution - 0099, São Paulo

625 00

Local Institution - 0069, Brno

656 53

Local Institution - 0067, Brno

779 00

Local Institution - 0068, Olomouc

07548

Local Institution - 0060, Gera

06120

Local Institution - 0058, Halle

00189

Local Institution - 0079, Roma

460-0001

Local Institution - 0169, Nagoya

277-8577

Local Institution - 0196, Kashiwa

811-1395

Local Institution - 0153, Fukuoka

951-8566

Local Institution - 0161, Niigata

589-8511

Local Institution - 0151, Ōsaka-sayama

591-8555

Local Institution - 0160, Sakai

362-0806

Local Institution - 0162, Kitaadachi-gun

641-8510

Local Institution - 0152, Wakayama

135-8550

Local Institution - 0154, Tokyo

0424

Local Institution - 0072, Oslo

82-300

Local Institution - 0044, Elblag

80-214

Local Institution - 0041, Gdansk

31-202

Local Institution - 0032, Krakow

93-513

Local Institution - 0033, Lodz

60-569

Local Institution - 0042, Poznan

02-781

Local Institution - 0035, Warsaw

020122

Local Institution - 0135, Bucharest

02841

Local Institution - 0147, Seoul

05505

Local Institution - 0148, Seoul

08025

Local Institution - 0006, Barcelona

08035

Local Institution - 0005, Barcelona

SW3 6JJ

Local Institution - 0157, London

M20 4XB

Local Institution - 0082, Manchester

ME16 9QQ

Local Institution - 0083, Maidstone

SM2 5PT

Local Institution - 0124, Sutton

SO16 6YD

Local Institution - 0123, Southampton

Sponsors
All Listed Sponsors
collaborator

Ono Pharmaceutical Co. Ltd

INDUSTRY

lead

Bristol-Myers Squibb

INDUSTRY