Chronic Cannabis Smoking, Oxidative Stress and the Pulmonary Innate Immune Response

RecruitingOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

November 11, 2015

Primary Completion Date

July 31, 2026

Study Completion Date

July 31, 2027

Conditions
Cannabis SmokingOxidative Stress
Interventions
PROCEDURE

Bronchoscopy

Passage of a thin flexible tube through the mouth, into the windpipe and then into the bronchial tubes so that the study doctor can look into the lungs to perform Bronchoalveolar lavage (BAL), cytologic brushing, and protected specimen brushing.

RADIATION

Chest X-ray

To identify any previously undiagnosed lung disease that will either increase the risk of bronchoscopy or confound results of the study.

PROCEDURE

Venipuncture

To collect blood cells and serum for analyses.

PROCEDURE

Intravenous Catheter

To administer the appropriate medications for the bronchoscopy procedure.

Trial Locations (1)

80045

RECRUITING

University of Colorado, Denver, Aurora

All Listed Sponsors
collaborator

National Center for Advancing Translational Sciences (NCATS)

NIH

lead

University of Colorado, Denver

OTHER