Clomiphene Citrate Versus Tamoxifen for Ovulation Induction in PCOs

PHASE4CompletedINTERVENTIONAL
Enrollment

600

Participants

Timeline

Start Date

June 30, 2015

Primary Completion Date

May 31, 2016

Study Completion Date

May 31, 2016

Conditions
PCOS
Interventions
DRUG

Clomiphene citrate

Women will receive one tablet of clomiphene citrate oral tablets 50 mg (Clomid®, aventis/Egypt) twice daily 12 hours apart (total dose 100 mg daily) from the 3rd day of the menses for 5 days, for only one menstrual cycle.

DRUG

Tamoxifen Placebo

Women will receive one tablet of placebo of tamoxifen oral tablets twice daily 12 hours apart from the 3rd day of the menses for 5 days, for only one menstrual cycle.

DRUG

Tamoxifen

Women will receive one tablet of tamoxifen oral tablets 10 mg (Tamoxifen®, amriya/Egypt) twice daily 12 hours apart (total dose 20 mg daily) from 3rd day of the menses for 5 days, for only one menstrual cycle.

DRUG

Clomiphene citrate placebo

Women will receive one tablet of placebo of clomiphene citrate twice daily 12 hours apart from 3rd day of the menses for 5 days, for only one menstrual cycle.

Trial Locations (1)

Unknown

Ain Shams University Maternity Hospital, Cairo

All Listed Sponsors
lead

Ain Shams University

OTHER

NCT02479256 - Clomiphene Citrate Versus Tamoxifen for Ovulation Induction in PCOs | Biotech Hunter | Biotech Hunter