NCT02477423View on ClinicalTrials.gov

A Randomized Controlled Trial Investigating if Antibiotic Use in the First 48 Hours of Life Adversely Impacts the Preterm Infant Microbiome

NACompletedINTERVENTIONAL
Enrollment

27

Participants

Timeline

Start Date

July 31, 2015

Primary Completion Date

June 30, 2019

Study Completion Date

June 30, 2019

Conditions
Premature Birth of NewbornEnterocolitis, Necrotizing
Interventions
DRUG

Ampicillin

Ampicillin will be given as routine antibiotic coverage for those in the active arm, as the standard initial antibiotic used within the neonatal unit. It may also be used for patients who are not eligible for randomization.

DRUG

Gentamicins

Gentamicin will be given as routine antibiotic coverage for those in the active arm, as the standard initial antibiotic used within the neonatal unit. It may also be used for patients who are not eligible for randomization.

DRUG

Placebo

Normal saline will be given as placebo for those in the placebo comparator group.

Trial Locations (1)

60637

University of Chicago Medical Center - Comer Children's Hospital, Chicago

All Listed Sponsors
lead

University of Chicago

OTHER

NCT02477423 - A Randomized Controlled Trial Investigating if Antibiotic Use in the First 48 Hours of Life Adversely Impacts the Preterm Infant Microbiome | Biotech Hunter | Biotech Hunter