Ultrasound Diaphragmatic Thickening to Monitor Its Dysfunction in Patients With Sepsis

NACompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

May 4, 2015

Primary Completion Date

July 8, 2019

Study Completion Date

April 1, 2020

Conditions
SepsisDisease of DiaphragmDefect of DiaphragmIntensive Care Neuropathy
Interventions
DEVICE

Diaphragmatic ultrasonography

"Daily Measure of Diaphragmatic Thickening Fraction (DTF) will be performed by a trained physiotherapist. Physiotherapist (A. LE NEINDRE). The patient will be then instructed to perform breathing to total lung capacity and then to exhale to residual volume, when it is possible (awaken patient). Awakening status will be recorded. Mechanically ventilated patients will be evaluated in Pressure Support (PS) mode (during daily PS mode research for patients with Controlled Ventilation), with the lower PS level tolerated. PS level will be recorded.~Thickening fraction (TF) measure is performed in B-mode using the following formula: TF (%) = \[(end-inspiration thickness - end-expiration thickness)/(end-expiration thickness) x 100\]. Diaphragmatic dysfunction is defined like a DTF \< 20% (7)."

Trial Locations (1)

75014

Groupe Hospitalier Paris Saint-Joseph, Paris

All Listed Sponsors
lead

Fondation Hôpital Saint-Joseph

OTHER

NCT02474797 - Ultrasound Diaphragmatic Thickening to Monitor Its Dysfunction in Patients With Sepsis | Biotech Hunter | Biotech Hunter