NCT02473263View on ClinicalTrials.gov

Samu Save Sepsis: Early Goal Directed Therapy in Pre Hospital Care of Patients With Severe Sepsis and/or Septic Shock

PHASE3CompletedINTERVENTIONAL
Enrollment

398

Participants

Timeline

Start Date

May 9, 2016

Primary Completion Date

February 9, 2019

Study Completion Date

February 9, 2019

Conditions
Severe Septic Syndrome (Severe Sepsis and Septic Shock) Diagnosed and Treated by Mobile Intensive Care Unit
Interventions
DRUG

Ceftriaxone

Ceftriaxone 2g IV will be infused in the first 60 minutes, for non nosocomial severe septic syndrome

DRUG

Piperacillin tazobactam

Piperacillin/tazobactam 4g IV will be infused in the first 60 minutes, for nosocomial severe septic syndrome

DRUG

Norepinephrine

Norepinephrine will be infused after failure of hemodynamic optimization using vascular fluid loading

DRUG

Hydrocortisone

Hydrocortisone 100mg IV will be infused after failure of hemodynamic optimization using norepinephrine with at least 1.5mg/h

Trial Locations (1)

75015

Anesthesiology, Intensive Care Unit and emergency department - Necker Hospital, Paris

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER

NCT02473263 - Samu Save Sepsis: Early Goal Directed Therapy in Pre Hospital Care of Patients With Severe Sepsis and/or Septic Shock | Biotech Hunter | Biotech Hunter