Dexmedetomidine for Sedation in Total Knee Replacements

PHASE3CompletedINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

June 30, 2015

Primary Completion Date

November 30, 2015

Study Completion Date

November 30, 2015

Conditions
Post-operative Pain for Total Knee Arthroplasty
Interventions
DRUG

Dexmedetomidine

Bolus dose prior to spinal anesthetic

DRUG

Bupivicaine

Intrathecal hyperbaric bupivicaine 12.75mg

DRUG

Normal Saline

Bolus 0.1cc/kg Normal Saline over 10 min

DRUG

Fentanyl

Intrathecal Fentanyl 10ug

DRUG

Midazolam

0-4mg of IV Midazolam prn for rescue sedation

Trial Locations (1)

S4S 0A5

Regina Qu'Appelle Health Region, Regina

All Listed Sponsors
lead

University of Saskatchewan

OTHER

NCT02466022 - Dexmedetomidine for Sedation in Total Knee Replacements | Biotech Hunter | Biotech Hunter