Role of Enhancing Serotonin Receptors Activity for Sleep Apnea Treatment in Patients With SCI

PHASE2CompletedINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

May 14, 2015

Primary Completion Date

April 12, 2019

Study Completion Date

April 12, 2019

Conditions
Spinal Cord InjurySleep Disordered Breathing
Interventions
DRUG

Buspirone

The initial dose of Buspirone is 15 mg daily (7.5 mg bid.). To achieve an optimal therapeutic response, at intervals of 2 to 3 days the dosage may be increased 5 mg per day until a maximum dose 30mg/day is reached.

DRUG

Trazodone

100 mg dose before bed-time

DRUG

Placebo

One placebo pill before bed-time

Trial Locations (1)

48201

John D. Dingell VA Medical Center, Detroit, MI, Detroit

All Listed Sponsors
lead

VA Office of Research and Development

FED

NCT02458469 - Role of Enhancing Serotonin Receptors Activity for Sleep Apnea Treatment in Patients With SCI | Biotech Hunter | Biotech Hunter