NCT02458339View on ClinicalTrials.gov

Methotrexate Infusion Into Fourth Ventricle in Children With Recurrent Malignant Fourth Ventricular Brain Tumors

PHASE1CompletedINTERVENTIONAL
Enrollment

7

Participants

Timeline

Start Date

June 15, 2015

Primary Completion Date

March 1, 2019

Study Completion Date

March 1, 2019

Conditions
Brain Tumor, RecurrentMalignant Neoplasm of Fourth Ventricle of Brain
Interventions
PROCEDURE

Ommaya Reservoir

Surgical catheter placement into the fourth ventricle of the brain

DRUG

Methotrexate

4, 6, or 8 mg into fourth ventricle of the brain via the Ommaya Reservoir for 2 days a week for 3 weeks with week 4 is a rest week. Each patient will undergo three cycles.

Trial Locations (1)

77030

UTHealth & Children's Memorial Hermann Hospital, Houston

All Listed Sponsors
lead

The University of Texas Health Science Center, Houston

OTHER

NCT02458339 - Methotrexate Infusion Into Fourth Ventricle in Children With Recurrent Malignant Fourth Ventricular Brain Tumors | Biotech Hunter | Biotech Hunter