The Safety and Immunogenicity of the DNA-GTU Vaccine Administered to HIV-infected Patients on ART vs Placebo

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

July 31, 2015

Primary Completion Date

July 31, 2016

Study Completion Date

July 31, 2016

Conditions
HIV
Interventions
BIOLOGICAL

GTU®-MultiHIV B Clade Vaccine

The investigational HIV-1 vaccine GTU®-MultiHIV B clade encodes for a MultiHIV antigen (synthetic fusion protein) built up by full-length polypeptides of Rev, Nef, Tat, p17 and p24 with more than 20 Th and CTL epitopes of protease, reverse transcriptase (RT) and gp160 regions of an HAN2 HIV-1 B clade isolate.

OTHER

Sodium chloride BP

For use in prophylactic and replacement therapy, requiring the use of isotonic saline solution.

Trial Locations (1)

W2 1PG

Imperial College London, Greater London

All Listed Sponsors
collaborator

European Commission

OTHER

lead

Imperial College London

OTHER

NCT02457689 - The Safety and Immunogenicity of the DNA-GTU Vaccine Administered to HIV-infected Patients on ART vs Placebo | Biotech Hunter | Biotech Hunter