Interaction of Sevoflurane Propofol and Remifentanil in Anesthesia for Laparoscopic Surgery

PHASE4CompletedINTERVENTIONAL
Enrollment

172

Participants

Timeline

Start Date

December 31, 2015

Primary Completion Date

October 23, 2023

Study Completion Date

October 23, 2023

Conditions
Drug InteractionsAnesthesia, Conduction
Interventions
DRUG

Propofol and Remifentanil

High propofol and low remifentanil, changing remifentanil (up-and-down method)

DRUG

Propofol and Remifentanil

Low propofol and high remifentanil, changing propofol (up-and-down method)

DRUG

Sevoflurane and Remifentanil

High sevoflurane and low remifentanil, changing remifentanil (up-and-down method)

DRUG

Sevoflurane and Remifentanil

Low sevoflurane and high remifentanil, changing sevoflurane up-and-down method)

DRUG

SPR 1

"Triple combination with intermediate propofol and sevoflurane and intermediate remifentanil.~SPR 1: Changing Propofol for skin incision."

DRUG

SPR2

"Triple combination with intermediate propofol and sevoflurane and intermediate remifentanil.~Changing Sevoflurane for skin incision."

Trial Locations (1)

3010

Department of Anesthesiology and Pain Therapy, Bern University Hospital, Bern

All Listed Sponsors
lead

Insel Gruppe AG, University Hospital Bern

OTHER

NCT02457442 - Interaction of Sevoflurane Propofol and Remifentanil in Anesthesia for Laparoscopic Surgery | Biotech Hunter | Biotech Hunter