32
Participants
Start Date
August 31, 2015
Primary Completion Date
September 30, 2017
Study Completion Date
December 31, 2017
Lab Work
Lab work to measure IL-7 and IL-7R
Certolizumab pegol (CDP870, tradename Cimzia)(prefilled syringes at the dose of 200mg)
"Certolizumab pegol (CDP870, tradename Cimzia) or is provided in prefilled syringes at the dose of 200mg.~Patients received 2x200mg at weeks 0, 2 and 4. Additionally a maintenance dose of 200mg is given every 2 weeks. Treatment is performed through subcutaneous injection."
Certolizumab pegol (CDP870, tradename Cimzia)
"rtolizumab pegol (CDP870, tradename Cimzia) or is provided in prefilled syringes at the dose of 200mg.~Patients received 2x200mg at weeks 0, 2 and 4. Additionally a maintenance dose of 200mg is given every 2 weeks. Treatment is performed through subcutaneous injection."
Hydroxychloroquine
some patients are on 400mg/day of hydroxychloroquine.
Sulfasalazine
some patients are on 300 mg/day and some patients are on 1000 mg/day dose of sulfasalazine
Medrol
some patients are on 8mg/day of medrol
Prednisone
some patients are on 10mg /day, some patients are on 20 mg/day, some patients are on 2.5 mg/day, some patients are on 30 mg/day, and some patients are on 5 mg/day of prednisone
Triamcinolone
some patients are on Triamcinolone 40-80mg IM monthly (received 40mg dose 1 week before blood draw, off enbrel 50mg weekly and SSZ 1000mg bid for \~ 3 months) some patients are on Triamcinolone 40mg IM monthly
Naproxen
some patients are on 1000 mg/day of naproxen
Leflunomide
some patients are on 20mg/day of leflunomide
Methotrexate
some patients are on 20mg weekly, some patients are on 25mg weekly, some patients are on 17.5 mg, some patients are on 15 mg weekly, some patients are on 7.5 mg weekly, and some patients are on 15 mg weekly dose of methotrexate
humira
some patients are on Humira 40mg q2weeks
Outpatient Care Center, Chicago
Collaborators (1)
UCB Pharma
INDUSTRY
University of Illinois at Chicago
OTHER