Xenodiagnosis After Antibiotic Treatment for Lyme Disease

NACompletedINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

July 24, 2015

Primary Completion Date

May 4, 2022

Study Completion Date

May 4, 2022

Conditions
Lyme Disease
Interventions
PROCEDURE

Skin biopsy

Optional 2-3mm skin punch biopsies will be performed.

PROCEDURE

Blood draw

Peripheral blood draws will be performed.

DEVICE

Xenodiagnosis

Larval ticks will be obtained from Dr. Sam Telford from a laboratory maintained tick colony at Tufts Veterinary School. These ticks are hatched from eggs laid by ticks that have fed only on specific pathogen free laboratory animals that were purchased from established vendors. Between 25-30 larval ticks that have been aged and are known to be ready to attach will be placed on the study participant.

Trial Locations (5)

10595

New York Medical College, Valhalla

20892

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda

06268

Mansfield Family Practice, Storrs

02111

Tufts Medical Center, Boston

11794-8153

Stony Brook University (State University of New York), Stony Brook

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Stony Brook University

OTHER

collaborator

Mansfield Family Practice LLC

OTHER

collaborator

Tufts Medical Center

OTHER

collaborator

New York Medical College

OTHER

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH