Safety of a Single Administration of AAV2hAQP1, an Adeno-Associated Viral Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in People With Irradiation-Induced Parotid Salivary Hypofunction

PHASE1Active, not recruitingINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

May 4, 2015

Primary Completion Date

July 31, 2026

Study Completion Date

July 31, 2026

Conditions

Squamous Cell Head and Neck CancerRadiation Induced XerostomiaSalivary Hypofunction

Interventions

BIOLOGICAL

AAV2hAQP1

Infusion of gene therapy

Trial Locations (1)

National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda