355
Participants
Start Date
April 30, 2015
Primary Completion Date
October 31, 2020
Study Completion Date
October 1, 2020
anisodamine
Anisodamine will be given first as bolus of 10 mg, followed by 0.1-0.5mg/kg/hr. The adjustment of pump infusion rate is largely at the discretion of treating physician, with the aim of improving microcirculation and limit the side effect to a minimum. For example, if serum lactate continues to elevate, the infusion rate can be increased. Discontinuation on severe side effect or recovery of shock (normalized lactate, weaned from vasopressor) or death.
department of critical care medicine, Ren Ji Hospital, School of medicine, Shanghai Jiao Tong University, Shanghai
the First Affiliated Hospital of Nanjing Medical University, Nanjing
Zhejiang Hospital, Hangzhou
Taizhou hospital of Zhejiang province, Taizhou
Sir Run Run Shaw hospital, Hangzhou
Jinhua Municipal Central Hospital, Jinhua
Department of critical care medicine, The central hospital of Lishui City, Lishui
Huizhou first hospital, Huizhou
Union Hospital, Tongji medical collegue, Huazhong university of Science and Technology, Wuhan
affiliated hospital, Jiangsu University, Zhenjiang
Binzhou People's hospital of Shandong province, Binzhou
Peace hospital of Changzhi medical college, Changzhi
The first People's hospital of Yongkang, Guli
Sir Run Run Shaw hospital, Hangzhou
Beilun People's hospital; The first affiliated hospital of Zhejiang university (Beilun Branch), Ningbo
Jinhua Central Hospital
OTHER