Uniform FDG-PET Guided Gradient Dose Prescription to Reduce Late Radiation Toxicity

PHASE3CompletedINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

June 30, 2016

Primary Completion Date

March 8, 2024

Study Completion Date

March 8, 2024

Conditions
Head and Neck NeoplasmsCarcinoma, Squamous Cell
Interventions
RADIATION

standard dose prescription

"* standard elective dose~* no intermediate dose-level~* visual interpretation of FDG-PET-scan"

RADIATION

FDG-PET guided gradient dose prescription

"* de-escalation of elective dose~* intermediate dose-level~* standardized methods to evaluate FDG-PET-scan"

Trial Locations (5)

Unknown

VU University Medical Center Amsterdam, Amsterdam

Radiotherapiegroep, Arnhem, Arnhem

MAASTRO clinic, Maastricht, Maastricht

Radboud University Nijmegen Medical Center, Nijmegen

University Medical Center Utrecht, Utrecht

All Listed Sponsors
collaborator

UMC Utrecht

OTHER

collaborator

Amsterdam UMC, location VUmc

OTHER

collaborator

Maastro Clinic, The Netherlands

OTHER

collaborator

Radiotherapiegroep

OTHER

lead

Radboud University Medical Center

OTHER

NCT02442375 - Uniform FDG-PET Guided Gradient Dose Prescription to Reduce Late Radiation Toxicity | Biotech Hunter | Biotech Hunter