The Effectiveness of Deep Brain Stimulation for Opioid Relapse Prevention

PHASE2/PHASE3UnknownINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

February 1, 2017

Primary Completion Date

July 31, 2019

Study Completion Date

July 31, 2021

Conditions
Opiate Addiction
Interventions
DEVICE

Suzhou Sceneray® DBS System

We plan to use the SceneRay 1242 (SceneRay, SuZhou, China) electrode with a diameter of 1.27 mm and 4 contacts. The SceneRay 1242 electrode combined with the SceneRay 1181 implantable pulse generator has the advantage of adaptive coverage area for the Ventral Capsule/Ventral Striatum, enabling simultaneous implantation in the nucleus accumbens (NAc; 2 ventral contacts) and the anterior limb of the internal capsule (ALIC; 2 dorsal contacts) with independently programmed parameters such as frequency, amplitude, and voltage; and remote and wireless programing, which allows for convenient and prompt adjustments in emergency situations. The contact length is 3.0 mm and the spacings between the ventral and dorsal contacts are 2 mm, 4 mm, and 4 mm, respectively, spanning a total length of 22.5 mm (3 + 2 + 3 + 4 + 3 + 4 + 3 mm, with 0.5 mm projecting from the electrode tip).

Trial Locations (2)

200025

RECRUITING

Shanghai RuiJin Hospital Psychitric Department, Shanghai

200030

RECRUITING

Shanghai Mental Health Center, Shanghai

Sponsors
All Listed Sponsors
collaborator

Suzhou Sceneray Medical Co. , Ltd

INDUSTRY

collaborator

Shanghai Mental Health Center

OTHER

collaborator

Institution of Neuroscience

UNKNOWN

collaborator

National Natural Science Foundation of China

OTHER_GOV

lead

Ruijin Hospital

OTHER