Effect of Desipramine on Upper Airway Collapsibility and Genioglossus Muscle Activity in Patients With Obstructive Sleep Apnea - Study B

PHASE2CompletedINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

April 30, 2015

Primary Completion Date

December 31, 2015

Study Completion Date

March 31, 2016

Conditions
Sleep Apnea, Obstructive
Interventions
DRUG

Desipramine

200 mg administered 2 hours before normal sleep time

DRUG

Placebo

Placebo-matching desipramine administered 2 hours before normal sleep time

Trial Locations (1)

02115

Sleep Disorders Research Program Brigham and Women's Hospital, Boston

All Listed Sponsors
lead

Brigham and Women's Hospital

OTHER

NCT02436031 - Effect of Desipramine on Upper Airway Collapsibility and Genioglossus Muscle Activity in Patients With Obstructive Sleep Apnea - Study B | Biotech Hunter | Biotech Hunter