Low-dose Ketamine vs Morphine for Vaso-occlusive Crisis in Sicklers

PHASE4CompletedINTERVENTIONAL
Enrollment

240

Participants

Timeline

Start Date

June 30, 2015

Primary Completion Date

January 31, 2016

Study Completion Date

February 29, 2016

Conditions
Sickle Cell CrisisAcute Pain
Interventions
DRUG

Low dose ketamine

Children in this arm shall receive a slow infusion of ketamine at a sub-anesthetic dose and monitored for pain, vital signs and side effects for 2 hours. Records will be taken at 5, 10, 20, 40, 60, 80, 100 and 120min.

DRUG

Morphine

Children in this arm shall receive intravenous infusion of morphine at analgesic dose and then monitored for pain, vital signs and side effects for 2 hours. Records will be taken at 5, 10, 20, 40, 60, 80, 100 and 120min.

Trial Locations (1)

256

Sickle Cell clinic, Mulago Hospital Complex, Kampala

All Listed Sponsors
lead

Makerere University

OTHER

NCT02434939 - Low-dose Ketamine vs Morphine for Vaso-occlusive Crisis in Sicklers | Biotech Hunter | Biotech Hunter