CryptoART Study: Decreasing Mortality Associated With Initiation of Antiretroviral Therapy in Sub-Saharan Africa

CompletedOBSERVATIONAL
Enrollment

1,333

Participants

Timeline

Start Date

April 30, 2015

Primary Completion Date

June 30, 2017

Study Completion Date

June 30, 2017

Conditions
Cryptococcal Meningitis
Interventions
OTHER

Pre-emptive screening and treatment for cryptococcal disease

Preemptive screening for cryptococcal disease among individuals with CD4 counts below 100 cells/mm3 with anti fungal therapy for those what are Cryptococcus antigen positive. These participants will be followed longitudinally for 12 months to determine clinical outcome, with their outcome compared with similar patients who are cryptococcal antigen negative, who will also be followed longitudinally for 12 months.

Trial Locations (1)

Unknown

Parirenyatwa Hospital, Harare

All Listed Sponsors
collaborator

Centers for Disease Control and Prevention

FED

lead

University of Zimbabwe

OTHER

NCT02434172 - CryptoART Study: Decreasing Mortality Associated With Initiation of Antiretroviral Therapy in Sub-Saharan Africa | Biotech Hunter | Biotech Hunter